BDBM50282851 (S)-2-[(S)-2-((S)-2-Mercaptomethyl-3-phenyl-propionylamino)-propionyl]-1,2,3,4-tetrahydro-isoquinoline-3-carboxylic acid::CHEMBL49920

SMILES C[C@H](NC(=O)[C@@H](CS)Cc1ccccc1)C(=O)N1Cc2ccccc2C[C@H]1C(O)=O

InChI Key InChIKey=UACOVYDVQRXMCG-BEVDRBHNSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50282851   

TargetAngiotensin-converting enzyme(Oryctolagus cuniculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50282851((S)-2-[(S)-2-((S)-2-Mercaptomethyl-3-phenyl-propio...)
Affinity DataIC50:  14nMAssay Description:In vitro inhibition of rabbit lung Angiotensin I converting enzyme (ACE) using Hippuryl-His-Leu as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
TargetNeprilysin(Homo sapiens (Human))TBA
LigandPNGBDBM50282851((S)-2-[(S)-2-((S)-2-Mercaptomethyl-3-phenyl-propio...)
Affinity DataIC50:  3.90nMAssay Description:Inhibition of neutral endopeptidase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetAngiotensin-converting enzyme(Homo sapiens (Human))TBA
LigandPNGBDBM50282851((S)-2-[(S)-2-((S)-2-Mercaptomethyl-3-phenyl-propio...)
Affinity DataIC50:  14nMAssay Description:Inhibition of angiotensin-converting enzyme (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetNeprilysin(Rattus norvegicus (Rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50282851((S)-2-[(S)-2-((S)-2-Mercaptomethyl-3-phenyl-propio...)
Affinity DataIC50:  3.90nMAssay Description:In vitro inhibition of rat kidney neutral endopeptidase (NEP) by fluorometric assay using Dansyl-Gly-Phe-Arg as substrateMore data for this Ligand-Target Pair
In DepthDetails Article