BDBM50283316 3'-Fluoro-4'-[6-(3-isopropyl-ureido)-4-oxo-2-propyl-4H-quinazolin-3-ylmethyl]-biphenyl-2-sulfonic acid (2-isobutoxy-acetyl)-amide::CHEMBL263191

SMILES CCCc1nc2ccc(NC(=O)NC(C)C)cc2c(=O)n1Cc1ccc(cc1F)-c1ccccc1S(=O)(=O)NC(=O)COCC(C)C

InChI Key InChIKey=DRRPFYALBDCXPZ-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50283316   

TargetType-1 angiotensin II receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50283316(3'-Fluoro-4'-[6-(3-isopropyl-ureido)-4-oxo-2-propy...)
Affinity DataIC50:  1.5nMAssay Description:In vivo inhibitory concentration of the compound against Angiotensin II receptor, type 1 of human adrenal membraneMore data for this Ligand-Target Pair
In DepthDetails Article
TargetType-2 angiotensin II receptor(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50283316(3'-Fluoro-4'-[6-(3-isopropyl-ureido)-4-oxo-2-propy...)
Affinity DataIC50:  0.380nMAssay Description:In vivo inhibitory concentration of the compound against AT2 receptor of rat adrenal membraneMore data for this Ligand-Target Pair
In DepthDetails Article
TargetType-2 angiotensin II receptor(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50283316(3'-Fluoro-4'-[6-(3-isopropyl-ureido)-4-oxo-2-propy...)
Affinity DataIC50:  1nMAssay Description:In vivo inhibitory concentration of the compound against AT2 receptor of rat adrenal membraneMore data for this Ligand-Target Pair
In DepthDetails Article
TargetType-2 angiotensin II receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50283316(3'-Fluoro-4'-[6-(3-isopropyl-ureido)-4-oxo-2-propy...)
Affinity DataIC50:  3.5nMAssay Description:In vivo inhibitory concentration of the compound against AT2 receptor of human adrenal membraneMore data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50283316(3'-Fluoro-4'-[6-(3-isopropyl-ureido)-4-oxo-2-propy...)
Affinity DataIC50:  0.170nMAssay Description:In vivo inhibitory concentration of the compound against Angiotensin II, type 2 of rat midbrain membraneMore data for this Ligand-Target Pair
In DepthDetails Article
TargetType-1 angiotensin II receptor(RABBIT)
TBA

Curated by ChEMBL
LigandPNGBDBM50283316(3'-Fluoro-4'-[6-(3-isopropyl-ureido)-4-oxo-2-propy...)
Affinity DataIC50:  0.520nMAssay Description:In vivo inhibitory concentration of the compound against Angiotensin II receptor, type 1 of rabbit aorta membraneMore data for this Ligand-Target Pair
In DepthDetails Article