BDBM50283765 CHEMBL321313::N-{3-[3-Butyl-4-(3-fluoro-2'-(ethyloxtycarbonyl)sulfamoyl-5'-propyl-biphenyl-4-ylmethyl)-5-oxo-4,5-dihydro-[1,2,4]triazol-1-yl]-4-chloro-phenyl}-acetamide

SMILES CCCCc1nn(-c2cc(NC(C)=O)ccc2Cl)c(=O)n1Cc1ccc(cc1F)-c1cc(CCC)ccc1S(=O)(=O)NC(=O)OCC

InChI Key InChIKey=AVPYNETYRCMACW-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50283765   

TargetType-1 angiotensin II receptor(RABBIT)
TBA

Curated by ChEMBL
LigandPNGBDBM50283765(CHEMBL321313 | N-{3-[3-Butyl-4-(3-fluoro-2'-(ethyl...)
Affinity DataIC50:  1.40nMAssay Description:In vitro ability of the compound to inhibit the binding of radioligand 125I[Sar1,IIe8]AII to AT1 receptor from rabbit aortaMore data for this Ligand-Target Pair
In DepthDetails Article
TargetType-2 angiotensin II receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50283765(CHEMBL321313 | N-{3-[3-Butyl-4-(3-fluoro-2'-(ethyl...)
Affinity DataIC50:  2.60nMAssay Description:In vitro inhibitory concentration of the compound against AT2 receptor from human adrenal tissues.More data for this Ligand-Target Pair
In DepthDetails Article
TargetType-1 angiotensin II receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50283765(CHEMBL321313 | N-{3-[3-Butyl-4-(3-fluoro-2'-(ethyl...)
Affinity DataIC50:  15nMAssay Description:In vitro inhibitory concentration of the compound against AT1 receptor from human adrenal tissues.More data for this Ligand-Target Pair
In DepthDetails Article
TargetType-2 angiotensin II receptor(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50283765(CHEMBL321313 | N-{3-[3-Butyl-4-(3-fluoro-2'-(ethyl...)
Affinity DataIC50:  0.100nMAssay Description:In vitro ability of the compound to inhibit the binding of radioligand 125I[Sar1,IIe8]AII to AT2 receptor from rat midbrainMore data for this Ligand-Target Pair
In DepthDetails Article