BDBM50284541 CHEMBL4174570

SMILES Cl.CC(C)C[C@H](NC(=O)[C@@H](O)[C@H](N)Cc1ccccc1)C(=O)OCn1cc(F)c(=O)[nH]c1=O

InChI Key InChIKey=PDPAMBMCZNAPSO-LPZNKSAJSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50284541   

TargetAminopeptidase N(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50284541(CHEMBL4174570)
Affinity DataIC50:  1.64E+5nMAssay Description:Inhibition of CD13 on surface of human PLC/PRF/5 cells using L-leucine-p-nitroanilide as substrate after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAminopeptidase N(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50284541(CHEMBL4174570)
Affinity DataIC50:  6.53E+4nMAssay Description:Inhibition of CD13 on surface of human ES2 cells using L-leucine-p-nitroanilide as substrate after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAminopeptidase N(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50284541(CHEMBL4174570)
Affinity DataIC50:  6.87E+4nMAssay Description:Inhibition of CD13 in human ES-2 cell surface using L-leucine-p-nitroanilide as substrate and measured after 1 hr by microplate reader analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAminopeptidase N(Sus scrofa (Pig))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50284541(CHEMBL4174570)
Affinity DataIC50:  6.98E+3nMAssay Description:Inhibition of porcine kidney microsomal CD13 using L-leucine-p-nitroanilide as substrate preincubated for 5 mins followed by substrate addition and m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAminopeptidase N(Sus scrofa (Pig))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50284541(CHEMBL4174570)
Affinity DataIC50:  3.18E+3nMAssay Description:Inhibition of porcine kidney CD13 using L-leucine-p-nitroanilide as substrate preincubated for 5 mins followed by substrate addition measured after 3...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed