BDBM50285580 CHEMBL4163892
SMILES CC[C@H]1N(C2CCCC2)c2nc(ncc2N(C)C1=O)-n1ccc2cc(ccc12)C(=O)NC
InChI Key InChIKey=TWYRQXNMQMYEGC-GOSISDBHSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50285580
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Hefei University Of Technology
Curated by ChEMBL
Hefei University Of Technology
Curated by ChEMBL
Affinity DataIC50: 94nMAssay Description:Inhibition human recombinant full length His-tagged Plk1 expressed in baculovirus expression system after 1 hr by FRET-based Z'-Lyte assayMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase PLK3(Homo sapiens (Human))
Hefei University Of Technology
Curated by ChEMBL
Hefei University Of Technology
Curated by ChEMBL
Affinity DataIC50: 7.15E+3nMAssay Description:Inhibition human recombinant GST-tagged Plk3 catalytic domain (58 to 340 residues) expressed in baculovirus expression system after 1 hr by FRET-base...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase PLK2(Homo sapiens (Human))
Hefei University Of Technology
Curated by ChEMBL
Hefei University Of Technology
Curated by ChEMBL
Affinity DataIC50: 8.60nMAssay Description:Inhibition human recombinant full length GST-tagged Plk2 expressed in baculovirus expression system after 1 hr by FRET-based Z'-Lyte assayMore data for this Ligand-Target Pair