BDBM50286329 2,6-Dichloro-benzoic acid 4-isopropyl-6-(4-methyl-piperazin-1-yl)-1,1,3-trioxo-1,3-dihydro-1lambda*6*-benzo[d]isothiazol-2-ylmethyl ester::CHEMBL333152

SMILES CC(C)c1cc(cc2c1C(=O)N(COC(=O)c1c(Cl)cccc1Cl)S2(=O)=O)N1CCN(C)CC1

InChI Key InChIKey=ASHIQHBFXYKICH-UHFFFAOYSA-N

Data  1 KI  2 Koff  1 Kon

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50286329   

TargetNeutrophil elastase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50286329(2,6-Dichloro-benzoic acid 4-isopropyl-6-(4-methyl-...)
Affinity DataKi:  1.10nMAssay Description:Evaluated for inhibitory activity against Human leukocyte elastase (HLE)More data for this Ligand-Target Pair
In DepthDetails Article
TargetNeutrophil elastase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50286329(2,6-Dichloro-benzoic acid 4-isopropyl-6-(4-methyl-...)
Affinity DataKon:  0.0000240M-1s-1 Koff:  2.15E+4s-1Assay Description:Evaluated for inhibitory activity against Human leukocyte elastase (HLE)More data for this Ligand-Target Pair
In DepthDetails Article
TargetNeutrophil elastase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50286329(2,6-Dichloro-benzoic acid 4-isopropyl-6-(4-methyl-...)
Affinity DataKon:  0.0000240M-1s-1Assay Description:Evaluated for inhibitory activity against Human leukocyte elastase (HLE)More data for this Ligand-Target Pair
In DepthDetails Article