BDBM50286671 2-[3-(2-Amino-ethyl)-1H-indol-5-yloxy]-1-[4-(3-methoxy-phenyl)-piperazin-1-yl]-ethanone::CHEMBL352234

SMILES COc1cccc(c1)N1CCN(CC1)C(=O)COc1ccc2[nH]cc(CCN)c2c1

InChI Key InChIKey=JXZFKONVCRZNRZ-UHFFFAOYSA-N

Data  3 KI  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50286671   

Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50286671(2-[3-(2-Amino-ethyl)-1H-indol-5-yloxy]-1-[4-(3-met...)
Affinity DataKi:  0.400nMAssay Description:Binding affinity towards cloned human 5-hydroxytryptamine 1D receptor alpha was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50286671(2-[3-(2-Amino-ethyl)-1H-indol-5-yloxy]-1-[4-(3-met...)
Affinity DataKi:  2nMAssay Description:Binding affinity towards cloned human 5-hydroxytryptamine 1D receptor beta was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50286671(2-[3-(2-Amino-ethyl)-1H-indol-5-yloxy]-1-[4-(3-met...)
Affinity DataKi:  9.80nMAssay Description:Compound was tested for its ability inhibit forskolin-stimulated activity of adenylate cyclase coupled to human 5-hydroxytryptamine 1D receptor beta ...More data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50286671(2-[3-(2-Amino-ethyl)-1H-indol-5-yloxy]-1-[4-(3-met...)
Affinity DataEC50:  0.240nMAssay Description:Compound was tested for its ability inhibit forskolin-stimulated activity of adenylate cyclase coupled to human 5-hydroxytryptamine 1D receptor beta ...More data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50286671(2-[3-(2-Amino-ethyl)-1H-indol-5-yloxy]-1-[4-(3-met...)
Affinity DataEC50:  85nMAssay Description:Compound was tested for its ability to inhibit forskolin-stimulated activity of adenylate cyclase coupled to human 5-HT 1A receptor in HeLa cells; va...More data for this Ligand-Target Pair
In DepthDetails Article