BDBM50287183 1-Benzo[1,3]dioxol-5-ylmethyl-3-(benzo[1,3]dioxol-5-ylsulfanyl)-5,6-dimethoxy-1H-indole-2-carboxylic acid::CHEMBL27732

SMILES COc1cc2c(Sc3ccc4OCOc4c3)c(C(O)=O)n(Cc3ccc4OCOc4c3)c2cc1OC

InChI Key InChIKey=NQDCDWVUSPOECA-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50287183   

TargetEndothelin receptor type B(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287183(1-Benzo[1,3]dioxol-5-ylmethyl-3-(benzo[1,3]dioxol-...)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of ET- 1 stimulated arachidonic acid release (AAR) in cultured rabbit renal vascular smooth muscle cells expressing the endothelin B recep...More data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-1 receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287183(1-Benzo[1,3]dioxol-5-ylmethyl-3-(benzo[1,3]dioxol-...)
Affinity DataIC50:  100nMAssay Description:Inhibition of ET- 1 stimulated arachidonic acid release (AAR) in cultured rabbit renal vascular smooth muscle cells expressing the endothelin A recep...More data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin receptor type B(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287183(1-Benzo[1,3]dioxol-5-ylmethyl-3-(benzo[1,3]dioxol-...)
Affinity DataIC50:  280nMAssay Description:Inhibition of ET- 1 stimulated arachidonic acid release (AAR) in cultured rabbit renal vascular smooth muscle cells expressing the endothelin A recep...More data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-1 receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287183(1-Benzo[1,3]dioxol-5-ylmethyl-3-(benzo[1,3]dioxol-...)
Affinity DataIC50:  5nMAssay Description:Affinity for human endothelin A receptor expressed in Ltk cells.More data for this Ligand-Target Pair
In DepthDetails Article