BDBM50287705 CHEMBL4169540

SMILES NC(=N)Nc1cccc(c1)C(=O)NCC(=O)N[C@@H](CC(O)=O)C(=O)NC(c1ccccc1)c1ccccc1

InChI Key InChIKey=QKCFDPUKGKJIML-NRFANRHFSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50287705   

TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50287705(CHEMBL4169540)
Affinity DataIC50:  1.40nMAssay Description:Inhibition of vitronectin binding to human alphaVbeta3 integrin after 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50287705(CHEMBL4169540)
Affinity DataIC50:  72nMAssay Description:Displacement of p53 from MDM2 in human U87MG cells incubated for 10 mins by sandwich ELISA methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein Mdm4(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50287705(CHEMBL4169540)
Affinity DataIC50:  77nMAssay Description:Displacement of p53 from MDM4 in human SHSY-5Y cells incubated for 10 mins by sandwich ELISA methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-5/beta-1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50287705(CHEMBL4169540)
Affinity DataIC50:  22nMAssay Description:Inhibition of fibronectin binding to soluble alpha5beta1 integrin (unknown origin) after 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed