BDBM50287952 CHEMBL304717::N-{4-[(2S,6R)-2-(tert-Butyl-dimethyl-silanyloxymethyl)-6-(4-chloro-6-methoxy-3-methyl-pyrazolo[3,4-b]quinolin-1-yl)-morpholine-4-sulfonyl]-phenyl}-acetamide

SMILES COc1ccc2nc3n(nc(C)c3c(Cl)c2c1)[C@H]1CN(C[C@@H](CO[Si](C)(C)C(C)(C)C)O1)S(=O)(=O)c1ccc(NC(C)=O)cc1

InChI Key InChIKey=HFIYWZSTTKASLB-WNCULLNHSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50287952   

TargetGTPase HRas(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287952(CHEMBL304717 | N-{4-[(2S,6R)-2-(tert-Butyl-dimethy...)
Affinity DataIC50:  2.70E+4nMAssay Description:Inhibition of nucleotide exchange process of oncogenic Ras in vitroMore data for this Ligand-Target Pair
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