BDBM50287961 (E)-5-[(2R,6R)-6-(4-Chloro-6-methoxy-3-methyl-pyrazolo[3,4-b]quinolin-1-yl)-4-(4-nitro-phenylsulfanyl)-morpholin-2-yl]-pent-3-en-2-one::CHEMBL59515

SMILES COc1ccc2nc3n(nc(C)c3c(Cl)c2c1)[C@H]1CN(C[C@H](O1)C=CCC(C)=O)Sc1ccc(cc1)[N+]([O-])=O

InChI Key InChIKey=LTDWFZQQPFUIBC-HYBUGGRVSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50287961   

TargetGTPase HRas(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287961((E)-5-[(2R,6R)-6-(4-Chloro-6-methoxy-3-methyl-pyra...)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of nucleotide exchange process of oncogenic Ras in vitroMore data for this Ligand-Target Pair
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