BDBM50290086 (R)-N*1*-[2,2-Dimethyl-1-((R)-methylcarbamoyl)-propyl]-N*4*-hydroxy-2-isobutyl-succinamide::CHEMBL306412::Ro-37-9790
SMILES CNC(=O)[C@H](NC(=O)[C@H](CC(C)C)CC(=O)NO)C(C)(C)C
InChI Key InChIKey=QRXOZHSEEGNRFC-PWSUYJOCSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50290086
Affinity DataIC50: 10nMAssay Description:Inhibition of human gelatinase B, MMP9More data for this Ligand-Target Pair
Target72 kDa type IV collagenase/Collagenase 3/Interstitial collagenase/Matrix metalloproteinase-9/Neutrophil collagenase(Homo sapiens (Human))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataIC50: 4.90nMAssay Description:Evaluation for functional inhibitory potency prevention of ET-1 induced constriction of rat aortic rings (ETA receptors)More data for this Ligand-Target Pair
Affinity DataIC50: 160nMAssay Description:Inhibition of human stromelysin-1, MMP-3More data for this Ligand-Target Pair