BDBM50291793 6,6-Dimethyl-1-(3-trifluoromethyl-phenyl)-1,6-dihydro-[1,3,5]triazine-2,4-diamine::CHEMBL6948
SMILES CC1(C)N=C(N)N=C(N)N1c1cccc(c1)C(F)(F)F
InChI Key InChIKey=MMFKOLPHNNHIDJ-UHFFFAOYSA-N
Data 8 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 8 hits for monomerid = 50291793
Affinity DataKi: 3.30nMAssay Description:Inhibitory activity against Lactobacillus casei dihydrofolate reductase (DHFR)More data for this Ligand-Target Pair
Affinity DataKi: 77.6nMAssay Description:Inhibition of dihydrofolate reductase from Pneumocystis carinii.More data for this Ligand-Target Pair
Affinity DataKi: 98nMAssay Description:Inhibitory activity against isolated chicken liver dihydrofolate reductase (DHFR)More data for this Ligand-Target Pair
Affinity DataKi: 130nMAssay Description:Inhibition of human DHFR using dihydrofolate as substrate after 180 secs by spectrophotometric analysisMore data for this Ligand-Target Pair
Affinity DataKi: 2.04E+3nMAssay Description:Inhibition constant against binding of Escherichia coli dihydrofolate reductaseMore data for this Ligand-Target Pair
Affinity DataKi: 2.04E+3nMAssay Description:Inhibition of Escherichia coli dihydrofolate reductase.More data for this Ligand-Target Pair
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Leishmania major)
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataKi: 2.19E+3nMAssay Description:Inhibition of dihydrofolate reductase (DHFR) from Leishmania majorChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 1.70E+4nMAssay Description:Inhibitory activity against Lactobacillus casei dihydrofolate reductase (DHFR)More data for this Ligand-Target Pair