BDBM50292848 1-Phosphono-4-[3-(4-fluorophenoxy)phenyl]butylsulfonic Acid Tripotassium Salt::CHEMBL461778

SMILES [O-]P([O-])(=O)C(CCCc1cccc(Oc2ccc(F)cc2)c1)S([O-])(=O)=O

InChI Key InChIKey=KVVRHSOKDFBFGC-UHFFFAOYSA-K

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50292848   

Target4,4'-diapophytoene synthase(Staphylococcus aureus)
University Of Illinois At Urbana-Champaign

Curated by ChEMBL
LigandPNGBDBM50292848(1-Phosphono-4-[3-(4-fluorophenoxy)phenyl]butylsulf...)
Affinity DataKi:  5nMAssay Description:Inhibition of Staphylococcus aureus dehydrosqualene synthase expressed in Escherichia coli BL21 (DE3) cells by continuous spectrophotometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Homo sapiens (Human))
University Of Illinois At Urbana-Champaign

Curated by ChEMBL
LigandPNGBDBM50292848(1-Phosphono-4-[3-(4-fluorophenoxy)phenyl]butylsulf...)
Affinity DataIC50:  17nMAssay Description:Inhibition of human recombinant squalene synthase expressed in Escherichia coli BL21 (DE3) cells assessed as formation of 1,10-dioic acid metabolite ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target4,4'-diapophytoene synthase(Staphylococcus aureus)
University Of Illinois At Urbana-Champaign

Curated by ChEMBL
LigandPNGBDBM50292848(1-Phosphono-4-[3-(4-fluorophenoxy)phenyl]butylsulf...)
Affinity DataIC50:  2.30E+3nMAssay Description:Inhibition of Staphylococcus aureus dehydrosqualene synthase expressed in Escherichia coli BL21 (DE3) cells by continuous spectrophotometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed