BDBM50293136 4-Chloro-17-Azapentacycle[6.6.5.0(2,7).0(9,14).0(15,19)]nonadeca-2,4,6,9(14),10,12-hexen-16,18-dione::CHEMBL475745

SMILES Clc1ccc2C3C4C(C(c5ccccc35)c2c1)C(=O)NC4=O

InChI Key InChIKey=UKJJKBLWMYINRP-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50293136   

TargetVoltage-dependent L-type calcium channel subunit alpha-1C(Mus musculus)
University Of Padova

Curated by ChEMBL
LigandPNGBDBM50293136(4-Chloro-17-Azapentacycle[6.6.5.0(2,7).0(9,14).0(1...)
Affinity DataIC50:  1.94E+4nMAssay Description:Inhibition of mouse brain L-type Cav1.2 channel by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1F(Homo sapiens (Human))
Alma Mater Studiorum-University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50293136(4-Chloro-17-Azapentacycle[6.6.5.0(2,7).0(9,14).0(1...)
Affinity DataIC50:  1.50E+4nMAssay Description:Inhibition of K+-induced voltage gated calcium channel opening in human SH-SY5Y cells assessed as decrease in Ca2+ level after 10 mins by Fluo-4 dye-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1F(Homo sapiens (Human))
Alma Mater Studiorum-University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50293136(4-Chloro-17-Azapentacycle[6.6.5.0(2,7).0(9,14).0(1...)
Affinity DataIC50:  1.50E+4nMAssay Description:Inhibition of K+-induced voltage gated calcium channel opening in human SH-SY5Y cells assessed as decrease in Ca2+ level after 10 mins by Fluo-4 dye-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed