BDBM50293539 1-(3-(5-(4-(aminomethyl)phenyl)-1H-pyrrolo[2,3-b]pyridin-3-yl)phenyl)-3-(2-phenoxyphenyl)urea::1-(3-{5-[4-(aminomethyl)phenyl]-1H-pyrrolo[2,3-b]pyridin-3-yl}phenyl)-3-(2-phenoxyphenyl)urea::CHEMBL563292

SMILES NCc1ccc(cc1)-c1cnc2[nH]cc(-c3cccc(NC(=O)Nc4ccccc4Oc4ccccc4)c3)c2c1

InChI Key InChIKey=KSTUYVHCHCYOAB-UHFFFAOYSA-N

Data  1 IC50

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50293539   

TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50293539(1-(3-(5-(4-(aminomethyl)phenyl)-1H-pyrrolo[2,3-b]p...)
Affinity DataIC50:  14nMAssay Description:Inhibition of GST-tagged human IGF1R expressed in Sf9-baculovirus systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed