BDBM50293544 CHEMBL554350::N,N-Dimethyl-3-(3-{3-[3-(2-phenoxy-phenyl)-ureido]-phenyl}-1H-pyrrolo[2,3-b]pyridin-5-yl)-benzenesulfonamide

SMILES CN(C)S(=O)(=O)c1cccc(c1)-c1cnc2[nH]cc(-c3cccc(NC(=O)Nc4ccccc4Oc4ccccc4)c3)c2c1

InChI Key InChIKey=XFYNIJCPJLZBEL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50293544   

TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50293544(CHEMBL554350 | N,N-Dimethyl-3-(3-{3-[3-(2-phenoxy-...)
Affinity DataIC50:  1.12E+3nMAssay Description:Inhibition of IGF1-induced human IGF1R phosphorylation expressed in mouse NIH-3T3 cells treated 2 hrs prior to IGF1 challenge by DELFIAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50293544(CHEMBL554350 | N,N-Dimethyl-3-(3-{3-[3-(2-phenoxy-...)
Affinity DataIC50:  57nMAssay Description:Inhibition of GST-tagged human IGF1R expressed in Sf9-baculovirus systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed