BDBM50293594 5-(2-amino-5-isobutylthiazol-4-yl)furan-2-ylphosphonic acid::CHEMBL495498

SMILES CC(C)Cc1sc(N)nc1-c1ccc(o1)P(O)(O)=O

InChI Key InChIKey=XJMYIJPPDSZOPN-UHFFFAOYSA-N

Data  7 IC50  1 EC50

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50293594   

TargetFructose-1,6-bisphosphatase 1(Homo sapiens (Human))
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50293594(5-(2-amino-5-isobutylthiazol-4-yl)furan-2-ylphosph...)
Affinity DataIC50:  10nMAssay Description:Inhibition of human liver FBPaseMore data for this Ligand-Target Pair
TargetFructose-1,6-bisphosphatase 1(Homo sapiens (Human))
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50293594(5-(2-amino-5-isobutylthiazol-4-yl)furan-2-ylphosph...)
Affinity DataIC50:  10nMAssay Description:Inhibition of human liver recombinant FBPaseMore data for this Ligand-Target Pair
TargetFructose-1,6-bisphosphatase 1(Homo sapiens (Human))
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50293594(5-(2-amino-5-isobutylthiazol-4-yl)furan-2-ylphosph...)
Affinity DataIC50:  16nMAssay Description:Inhibition of human liver FBPase 1More data for this Ligand-Target Pair
TargetFructose-1,6-bisphosphatase 1(Homo sapiens (Human))
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50293594(5-(2-amino-5-isobutylthiazol-4-yl)furan-2-ylphosph...)
Affinity DataIC50:  16nMAssay Description:Inhibition of human liver FBPase expressed in Escherichia coliMore data for this Ligand-Target Pair
TargetFructose-1,6-bisphosphatase 1(Homo sapiens (Human))
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50293594(5-(2-amino-5-isobutylthiazol-4-yl)furan-2-ylphosph...)
Affinity DataIC50:  25nMAssay Description:Inhibition of human liver FBPMore data for this Ligand-Target Pair
TargetFructose-1,6-bisphosphatase 1(Homo sapiens (Human))
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50293594(5-(2-amino-5-isobutylthiazol-4-yl)furan-2-ylphosph...)
Affinity DataIC50:  44nMAssay Description:Inhibition of human liver FBPase expressed in Escherichia coli BL21(DE3) using FBP as substrate in presence of PGI and G6PDH by spectrophotometric me...More data for this Ligand-Target Pair
TargetFructose-1,6-bisphosphatase 1(Homo sapiens (Human))
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50293594(5-(2-amino-5-isobutylthiazol-4-yl)furan-2-ylphosph...)
Affinity DataIC50:  25nMAssay Description:Inhibition of human liver FBPase expressed in Escherichia coli by spectrophotometric methodMore data for this Ligand-Target Pair
TargetFructose-1,6-bisphosphatase 1(Homo sapiens (Human))
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50293594(5-(2-amino-5-isobutylthiazol-4-yl)furan-2-ylphosph...)
Affinity DataEC50:  16nMAssay Description:Inhibition of human liver FBPaseMore data for this Ligand-Target Pair