BDBM50293653 (4-methylpiperazin-1-yl)(6-(2-phenylethynyl)pyridin-3-yl)methanone::CHEMBL564781

SMILES CN1CCN(CC1)C(=O)c1ccc(nc1)C#Cc1ccccc1

InChI Key InChIKey=BASZDIYJQVPYAG-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50293653   

TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50293653((4-methylpiperazin-1-yl)(6-(2-phenylethynyl)pyridi...)
Affinity DataEC50:  1.60E+3nMAssay Description:Agonist activity at human mGluR5 transiently transfected in BHK cells assessed as potentiation of L-glutamate-induced calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed