BDBM50293749 1-(2,3-dimethoxybenzyl)-2-(4-sulfamoylphenylamino)-1H-benzo[d]imidazole-5-carboxamide::CHEMBL564451

SMILES COc1cccc(Cn2c(Nc3ccc(cc3)S(N)(=O)=O)nc3cc(ccc23)C(N)=O)c1OC

InChI Key InChIKey=RPCHBCSSYSNRNY-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50293749   

TargetKinesin-like protein KIF11(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50293749(1-(2,3-dimethoxybenzyl)-2-(4-sulfamoylphenylamino)...)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibition of human kinesin spindle protein by endpoint assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKinesin heavy chain isoform 5A(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50293749(1-(2,3-dimethoxybenzyl)-2-(4-sulfamoylphenylamino)...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of nKHCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKinesin-like protein KIF3B(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50293749(1-(2,3-dimethoxybenzyl)-2-(4-sulfamoylphenylamino)...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of Kif3BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed