BDBM50293959 (R)-5-Chloro-1-(1-cyclopropyl-2-methoxyethyl)-3-(2,4,6-trimethylphenylamino)pyrazin-2(1H)-one::CHEMBL549875

SMILES COC[C@@H](C1CC1)n1cc(Cl)nc(Nc2c(C)cc(C)cc2C)c1=O

InChI Key InChIKey=FSUVRTLZOIFIJT-HNNXBMFYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50293959   

TargetCorticotropin-releasing factor receptor 1(Rattus norvegicus (rat))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50293959((R)-5-Chloro-1-(1-cyclopropyl-2-methoxyethyl)-3-(2...)
Affinity DataIC50:  1.30nMAssay Description:Displacement of [125I]Tyr-ovine-CRF from CRF1 receptor in rat frontal cortex homogenate by gamma countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed