BDBM50293966 (S)-3,5-dichloro-4-(6-chloro-4-(1-cyclopropylethyl)-3-oxo-3,4-dihydropyrazin-2-ylamino)benzonitrile::CHEMBL565144

SMILES C[C@@H](C1CC1)n1cc(Cl)nc(Nc2c(Cl)cc(cc2Cl)C#N)c1=O

InChI Key InChIKey=PMRNKYWNCWTMBT-QMMMGPOBSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50293966   

TargetCorticotropin-releasing factor receptor 1(Rattus norvegicus (rat))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50293966((S)-3,5-dichloro-4-(6-chloro-4-(1-cyclopropylethyl...)
Affinity DataIC50:  6.30nMAssay Description:Displacement of [125I]Tyr-ovine-CRF from CRF1 receptor in rat frontal cortex homogenate by gamma countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed