BDBM50293971 (R)-5-Chloro-1-(1-cyclopropylpropyl)-3-(2,4-dimethylphenylamino)-pyrazin-2(1H)-one::CHEMBL560633

SMILES CC[C@H](C1CC1)n1cc(Cl)nc(Nc2ccc(C)cc2C)c1=O

InChI Key InChIKey=JJVYIIRLCMXUQJ-OAHLLOKOSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50293971   

TargetCorticotropin-releasing factor receptor 1(Rattus norvegicus (rat))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50293971((R)-5-Chloro-1-(1-cyclopropylpropyl)-3-(2,4-dimeth...)
Affinity DataIC50:  6.60nMAssay Description:Displacement of [125I]Tyr-ovine-CRF from CRF1 receptor in rat frontal cortex homogenate by gamma countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed