BDBM50293976 (R)-3-[4-(Benzyloxy)-2,5-dimethylphenylamino]-5-chloro-1-(1-cyclopropyl-2-methoxyethyl)pyrazin-2(1H)-one::CHEMBL561034

SMILES COC[C@@H](C1CC1)n1cc(Cl)nc(Nc2cc(C)c(OCc3ccccc3)cc2C)c1=O

InChI Key InChIKey=UOYOEDPYDZLMAS-NRFANRHFSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50293976   

TargetCorticotropin-releasing factor receptor 1(Rattus norvegicus (rat))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50293976((R)-3-[4-(Benzyloxy)-2,5-dimethylphenylamino]-5-ch...)
Affinity DataIC50:  910nMAssay Description:Displacement of [125I]Tyr-ovine-CRF from CRF1 receptor in rat frontal cortex homogenate by gamma countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed