BDBM50293978 (R)-5-Chloro-1-(1-cyclopropylpropyl)-3-[ethyl(2,4,5-trimethylphenyl)amino]pyrazin-2(1H)-one::CHEMBL552559

SMILES CC[C@H](C1CC1)n1cc(Cl)nc(N(CC)c2cc(C)c(C)cc2C)c1=O

InChI Key InChIKey=KGUVKVMTPQMGGN-QGZVFWFLSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50293978   

TargetCorticotropin-releasing factor receptor 1(Rattus norvegicus (rat))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50293978((R)-5-Chloro-1-(1-cyclopropylpropyl)-3-[ethyl(2,4,...)
Affinity DataIC50:  1.5nMAssay Description:Displacement of [125I]Tyr-ovine-CRF from CRF1 receptor in rat frontal cortex homogenate by gamma countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed