BDBM50293984 (R)-1-(1-Cyclopropylethyl)-3-[6-methoxy-2-(trifluoromethyl)-pyridin-3-ylamino]pyrazin-2(1H)-one::CHEMBL564291

SMILES COc1ccc(Nc2nccn([C@H](C)C3CC3)c2=O)c(n1)C(F)(F)F

InChI Key InChIKey=OWMQCDOIWCGTGY-SECBINFHSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50293984   

TargetCorticotropin-releasing factor receptor 1(Rattus norvegicus (rat))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50293984((R)-1-(1-Cyclopropylethyl)-3-[6-methoxy-2-(trifluo...)
Affinity DataIC50:  150nMAssay Description:Displacement of [125I]Tyr-ovine-CRF from CRF1 receptor in rat frontal cortex homogenate by gamma countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed