BDBM50293990 (R)-1-(1-Cyclopropylethyl)-5-ethyl-3-[6-methoxy-2-(trifluoromethyl)pyridin-3-ylamino]pyrazin-2(1H)-one::CHEMBL561226

SMILES CCc1cn([C@H](C)C2CC2)c(=O)c(Nc2ccc(OC)nc2C(F)(F)F)n1

InChI Key InChIKey=VMIKDMQTPYASCX-SNVBAGLBSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50293990   

TargetCorticotropin-releasing factor receptor 1(Rattus norvegicus (rat))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50293990((R)-1-(1-Cyclopropylethyl)-5-ethyl-3-[6-methoxy-2-...)
Affinity DataIC50:  180nMAssay Description:Displacement of [125I]Tyr-ovine-CRF from CRF1 receptor in rat frontal cortex homogenate by gamma countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed