BDBM50294064 4-[6-((3aR,6aR)-5-Methyl-hexahydro-pyrrolo[3,4-b]pyrrol-1-yl)-naphthalen-2-yl]-benzonitrile::CHEMBL549470

SMILES CN1C[C@H]2CCN([C@H]2C1)c1ccc2cc(ccc2c1)-c1ccc(cc1)C#N

InChI Key InChIKey=SVNFUPXRBVBNHU-VWNXMTODSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50294064   

TargetHistamine H3 receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50294064(4-[6-((3aR,6aR)-5-Methyl-hexahydro-pyrrolo[3,4-b]p...)
Affinity DataKi:  4.20nMAssay Description:Displacement of [3H]N-alpha methyl histamine from human cloned histamine H3 receptor expressed in C6 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Rattus norvegicus (rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50294064(4-[6-((3aR,6aR)-5-Methyl-hexahydro-pyrrolo[3,4-b]p...)
Affinity DataKi:  64.6nMAssay Description:Displacement of [3H]N-alpha methyl histamine from rat cortical membrane histamine H3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed