BDBM50294125 (E)-2-(4-(2-(Biphenyl-4-yl)vinyl)-N-isopropoxyphenylsulfonamido)-N-hydroxyacetamide::CHEMBL563679

SMILES CC(C)ON(CC(=O)NO)S(=O)(=O)c1ccc(\C=C\c2ccc(cc2)-c2ccccc2)cc1

InChI Key InChIKey=ZQBRASLBYJYZLM-CMDGGOBGSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50294125   

TargetMatrix metalloproteinase-14(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50294125((E)-2-(4-(2-(Biphenyl-4-yl)vinyl)-N-isopropoxyphen...)
Affinity DataIC50:  2.80E+3nMAssay Description:Inhibition of human recombinant MMP14More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50294125((E)-2-(4-(2-(Biphenyl-4-yl)vinyl)-N-isopropoxyphen...)
Affinity DataIC50:  2.30E+3nMAssay Description:Inhibition of MMP9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50294125((E)-2-(4-(2-(Biphenyl-4-yl)vinyl)-N-isopropoxyphen...)
Affinity DataIC50:  5.60E+3nMAssay Description:Inhibition of MMP1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50294125((E)-2-(4-(2-(Biphenyl-4-yl)vinyl)-N-isopropoxyphen...)
Affinity DataIC50:  41nMAssay Description:Inhibition of MMP13-mediated collagen degradation by SDS-PAGEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50294125((E)-2-(4-(2-(Biphenyl-4-yl)vinyl)-N-isopropoxyphen...)
Affinity DataIC50:  710nMAssay Description:Inhibition of MMP3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50294125((E)-2-(4-(2-(Biphenyl-4-yl)vinyl)-N-isopropoxyphen...)
Affinity DataIC50:  3.60E+3nMAssay Description:Inhibition of MMP8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50294125((E)-2-(4-(2-(Biphenyl-4-yl)vinyl)-N-isopropoxyphen...)
Affinity DataIC50:  74nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed