BDBM50294494 2-amino-4-(((2S,3S,4R,5R)-3,4-dihydroxy-5-(6-(3-phenylpropylamino)-9H-purin-9-yl)-tetrahydrofuran-2-yl)methylthio)butanoic acid::CHEMBL560105

SMILES NC(CCSC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(NCCCc3ccccc3)ncnc12)C(O)=O

InChI Key InChIKey=QAVAAPUGVSFKKD-SYDIUPFYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50294494   

TargetDNA (cytosine-5)-methyltransferase 3B(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50294494(2-amino-4-(((2S,3S,4R,5R)-3,4-dihydroxy-5-(6-(3-ph...)
Affinity DataIC50:  600nMAssay Description:Inhibition of human recombinant DNMT3b2 expressed in baculovirus infected high five insect cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA (cytosine-5)-methyltransferase 1(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50294494(2-amino-4-(((2S,3S,4R,5R)-3,4-dihydroxy-5-(6-(3-ph...)
Affinity DataIC50:  7.40E+3nMAssay Description:Inhibition of human recombinant DNMT1 expressed in baculovirus infected high five insect cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed