BDBM50294573 (2R,3R,4S,5S)-2-(6-amino-9H-purin-9-yl)-5-((2-aminoethylthio)methyl)tetrahydrofuran-3,4-diol::5'-(Aminoethylthio)-5'-deoxy-adenosine::5'-DEOXY-5'-[2-(AMINO)ETHYLTHIO]ADENOSINE::CHEMBL563938
SMILES NCCSC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N)ncnc12
InChI Key InChIKey=APAPOJUCRZTCHD-WOUKDFQISA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50294573
TargetHistone-lysine N-methyltransferase, H3 lysine-79 specific(Homo sapiens (Human))
Baylor College Of Medicine
Curated by ChEMBL
Baylor College Of Medicine
Curated by ChEMBL
Affinity DataKi: 2.50E+4nMAssay Description:Inhibition of human recombinant DOT1L catalytic domain amino acid (1 to 472) using [3H]-SAM after 30 mins by scintillation counterMore data for this Ligand-Target Pair
TargetPhenylethanolamine N-methyltransferase(Homo sapiens (Human))
University Of Kansas
Curated by ChEMBL
University Of Kansas
Curated by ChEMBL
Affinity DataKi: 2.80E+4nMAssay Description:Competitive inhibition of C-terminal hexahistidine tag in human recombinant PNMT expressed in Escherichia coli assessed as inhibition constant using ...More data for this Ligand-Target Pair
Affinity DataKi: 1.10E+6nMAssay Description:Displacement of [3H]-clonidine from Sprague-Dawley rat alpha2 adrenergic receptor by radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 4.10E+4nMAssay Description:Inhibition of human recombinant DNMT3b2More data for this Ligand-Target Pair
Affinity DataIC50: 1.80E+4nMAssay Description:Inhibition of human recombinant DNMT1More data for this Ligand-Target Pair