BDBM50295813 12,13-(1,6-hex-cis-3-enyl)-6,7,12,13-tetrahydro-5-oxo-5H-indolo[2,3-a]pyrrolo[3,4-c]carbazole::CHEMBL558115

SMILES O=C1NCc2c1c1c3ccccc3n3CC\C=C/CCn4c5ccccc5c2c4c13

InChI Key InChIKey=OLEJJFVQPXRZGL-UPHRSURJSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50295813   

TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50295813(12,13-(1,6-hex-cis-3-enyl)-6,7,12,13-tetrahydro-5-...)
Affinity DataIC50:  39nMAssay Description:Inhibition of JAK3 expressed in insect Sf21 cells assessed as inhibition of biotinylated substrate phosphorylationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed