BDBM50295816 (16S,17R)-16-{[3-(dimethylamino)pyrrolidin-1-yl]carbonyl}-16,17-dihydroxy-4,14,19-triazaheptacyclo[12.11.2.0^{2,6}.0^{7,27}.0^{8,13}.0^{19,26}.0^{20,25}]heptacosa-1,6,8(13),9,11,20(25),21,23,26-nonaene-3,5-dione::CHEMBL557559
SMILES CN(C)C1CCN(C1)C(=O)[C@]1(O)Cn2c3ccccc3c3c4C(=O)NC(=O)c4c4c5ccccc5n(C[C@H]1O)c4c23
InChI Key InChIKey=LHYZJPGCHNNXRH-YFPVIJNISA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 50295816
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Affinity DataIC50: 15nMAssay Description:Inhibition of JAK3 expressed in insect Sf21 cells assessed as inhibition of biotinylated substrate phosphorylationMore data for this Ligand-Target Pair