BDBM50295885 5-(biphenyl-4-yl)-4-(1-methyl-1H-indol-3-yl)pyrimidin-2-amine::CHEMBL559538

SMILES Cn1cc(-c2nc(N)ncc2-c2ccc(cc2)-c2ccccc2)c2ccccc12

InChI Key InChIKey=CVIMBUQNJRLCFV-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50295885   

TargetCyclin-dependent kinase 5(Homo sapiens (Human))
Clermont Universit£

Curated by ChEMBL
LigandPNGBDBM50295885(5-(biphenyl-4-yl)-4-(1-methyl-1H-indol-3-yl)pyrimi...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human recombinant CDK5/p25More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 1(Rattus norvegicus (rat))
Clermont Universit£

Curated by ChEMBL
LigandPNGBDBM50295885(5-(biphenyl-4-yl)-4-(1-methyl-1H-indol-3-yl)pyrimi...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of rat recombinant Erk2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50295885(5-(biphenyl-4-yl)-4-(1-methyl-1H-indol-3-yl)pyrimi...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of rat recombinant DYRK1A expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed