BDBM50295953 2-Chloro-3-(2-fluoro-4-(pyridinyl)methoxy)-5-(2-(S)-pyrrolidinyl)methoxy)-pyridine::CHEMBL560788

SMILES Fc1cc(COc2cc(OC[C@@H]3CCCN3)cnc2Cl)ccn1

InChI Key InChIKey=CRYOUEVORXBVRJ-LBPRGKRZSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50295953   

TargetNeuronal acetylcholine receptor subunit alpha-2(Rattus norvegicus (Rat))
The Johns Hopkins University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50295953(2-Chloro-3-(2-fluoro-4-(pyridinyl)methoxy)-5-(2-(S...)
Affinity DataKi:  0.0350nMAssay Description:Displacement of [3H]epibatidine from rat alpha2beta2 nicotinic receptor expressed in human HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-4(Rattus norvegicus (Rat))
The Johns Hopkins University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50295953(2-Chloro-3-(2-fluoro-4-(pyridinyl)methoxy)-5-(2-(S...)
Affinity DataKi:  0.130nMAssay Description:Displacement of [3H]epibatidine from rat alpha4beta2 nicotinic receptor expressed in human HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-3(Rattus norvegicus (Rat))
The Johns Hopkins University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50295953(2-Chloro-3-(2-fluoro-4-(pyridinyl)methoxy)-5-(2-(S...)
Affinity DataKi:  0.25nMAssay Description:Displacement of [3H]epibatidine from rat alpha3beta2 nicotinic receptor expressed in human HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-4(Rattus norvegicus (Rat))
The Johns Hopkins University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50295953(2-Chloro-3-(2-fluoro-4-(pyridinyl)methoxy)-5-(2-(S...)
Affinity DataKi:  1.10nMAssay Description:Displacement of [3H]epibatidine from rat alpha4beta4 nicotinic receptor expressed in human HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-2(Rattus norvegicus (Rat))
The Johns Hopkins University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50295953(2-Chloro-3-(2-fluoro-4-(pyridinyl)methoxy)-5-(2-(S...)
Affinity DataKi:  8.20nMAssay Description:Displacement of [3H]epibatidine from rat alpha2beta4 nicotinic receptor expressed in human HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-3(Rattus norvegicus (Rat))
The Johns Hopkins University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50295953(2-Chloro-3-(2-fluoro-4-(pyridinyl)methoxy)-5-(2-(S...)
Affinity DataKi:  43nMAssay Description:Displacement of [3H]epibatidine from rat alpha3beta4 nicotinic receptor expressed in human HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed