BDBM50296043 CHEMBL540930::N-((5-chloro-6-oxo-1,6-dihydropyridin-3-yl)(4-fluorophenyl)methyl)-2-(1-((1-(4-(trifluoromethyl)phenyl)-1H-pyrrol-3-yl)methyl)piperidin-4-yl)acetamide

SMILES Fc1ccc(cc1)C(NC(=O)CC1CCN(Cc2ccn(c2)-c2ccc(cc2)C(F)(F)F)CC1)c1c[nH]c(=O)c(Cl)c1

InChI Key InChIKey=ACHAGBFZZOHGJZ-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50296043   

TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Astrazeneca R & D M£Lndal

Curated by ChEMBL
LigandPNGBDBM50296043(CHEMBL540930 | N-((5-chloro-6-oxo-1,6-dihydropyrid...)
Affinity DataIC50: >3.16E+4nMAssay Description:Inhibition of human ERG expressed in CHO cells by patch clamp assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Astrazeneca R & D M£Lndal

Curated by ChEMBL
LigandPNGBDBM50296043(CHEMBL540930 | N-((5-chloro-6-oxo-1,6-dihydropyrid...)
Affinity DataIC50:  6nMAssay Description:Displacement of [125I]MCH from human MCHR1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Astrazeneca R & D M£Lndal

Curated by ChEMBL
LigandPNGBDBM50296043(CHEMBL540930 | N-((5-chloro-6-oxo-1,6-dihydropyrid...)
Affinity DataIC50:  21nMAssay Description:Antagonist activity at human MCHR1 expressed in HEK293 cells assessed as [35S]GTPgammaS accumulationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 2(Homo sapiens (Human))
Astrazeneca R & D M£Lndal

Curated by ChEMBL
LigandPNGBDBM50296043(CHEMBL540930 | N-((5-chloro-6-oxo-1,6-dihydropyrid...)
Affinity DataIC50:  4.60E+3nMAssay Description:Displacement of [125I]MCH from human MCHR2 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))
Astrazeneca R & D M£Lndal

Curated by ChEMBL
LigandPNGBDBM50296043(CHEMBL540930 | N-((5-chloro-6-oxo-1,6-dihydropyrid...)
Affinity DataIC50: >3.16E+4nMAssay Description:Inhibition of NaV1.5 sodium channel expressed in CHO cells by patch clamp assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed