BDBM50296641 1-(2,5-difluorophenyl)-7-methyl-4-(4-methylpyridin-3-ylamino)-1H-pyrazolo[3,4-b]pyridin-6(7H)-one::CHEMBL563091

SMILES Cc1ccncc1Nc1cc(=O)n(C)c2n(ncc12)-c1cc(F)ccc1F

InChI Key InChIKey=SHTNULYTFRAXDF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50296641   

TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50296641(1-(2,5-difluorophenyl)-7-methyl-4-(4-methylpyridin...)
Affinity DataIC50:  444nMAssay Description:Inhibition of human recombinant p38alpha assessed as phosphorylation of ATF2 by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed