BDBM50296658 CHEMBL561468::N-cyclopropyl-3-(1-(2,5-difluorophenyl)-7-methyl-6-oxo-6,7-dihydro-1H-pyrazolo[3,4-b]pyridin-4-yloxy)-4-methylbenzamide

SMILES Cc1ccc(cc1Oc1cc(=O)n(C)c2n(ncc12)-c1cc(F)ccc1F)C(=O)NC1CC1

InChI Key InChIKey=IDHQVXAUCQYHMN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50296658   

TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50296658(CHEMBL561468 | N-cyclopropyl-3-(1-(2,5-difluorophe...)
Affinity DataIC50:  6.10nMAssay Description:Inhibition of human recombinant p38alpha assessed as phosphorylation of ATF2 by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed