BDBM50296662 CHEMBL559242::N-cyclopropyl-3-(1-(2,6-difluorophenyl)-7-methyl-6-oxo-6,7-dihydro-1H-pyrazolo[3,4-b]pyridin-4-ylamino)-4-fluorobenzamide

SMILES Cn1c2n(ncc2c(Nc2cc(ccc2F)C(=O)NC2CC2)cc1=O)-c1c(F)cccc1F

InChI Key InChIKey=LULPDPCVNZTIIV-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50296662   

TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50296662(CHEMBL559242 | N-cyclopropyl-3-(1-(2,6-difluorophe...)
Affinity DataIC50:  1.90nMAssay Description:Inhibition of human recombinant p38alpha assessed as phosphorylation of ATF2 by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed