BDBM50296685 (3,4-dimethylphenyl)(4-phenoxyphenyl)methanone::CHEMBL557722

SMILES Cc1ccc(cc1C)C(=O)c1ccc(Oc2ccccc2)cc1

InChI Key InChIKey=WAJARHMGAQFYHB-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50296685   

TargetMetabotropic glutamate receptor 1(RAT)
Merz Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50296685((3,4-dimethylphenyl)(4-phenoxyphenyl)methanone | C...)
Affinity DataKi: >4.00E+4nMAssay Description:Displacement of [3H]E-3-(2-chloro-8-methylquinolin-3-yl)-1-(thiophen-2-yl)prop-2-en-1-one from mGluR1 in rat cerebellar membrane after 14 to 16 hrs b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 1(RAT)
Merz Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50296685((3,4-dimethylphenyl)(4-phenoxyphenyl)methanone | C...)
Affinity DataIC50:  1.53E+4nMAssay Description:Allosteric antagonist activity at mGluR1 in Sprague-Dawley rat cerebellar granule cells assessed as accumulation of [3H]inositol phosphate by liquid ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed