BDBM50296954 (Z)-5-(4-bromo-2-fluorophenyl)-3-phenylpent-2-enoic acid::CHEMBL552276

SMILES OC(=O)\C=C(\CCc1ccc(Br)cc1F)c1ccccc1

InChI Key InChIKey=TXZZTTXGFQGOTL-UVTDQMKNSA-N

Data  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50296954   

Target3-phosphoinositide-dependent protein kinase 1(Homo sapiens (Human))
Universit£Tsklinikum Frankfurt

Curated by ChEMBL
LigandPNGBDBM50296954((Z)-5-(4-bromo-2-fluorophenyl)-3-phenylpent-2-enoi...)
Affinity DataKd:  6.20E+3nMAssay Description:Binding affinity to human PDPK1 Y288G/Q292A mutant expressed in insect cell system assessed as substrate phosphorylation by isothermal titration calo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-phosphoinositide-dependent protein kinase 1(Homo sapiens (Human))
Universit£Tsklinikum Frankfurt

Curated by ChEMBL
LigandPNGBDBM50296954((Z)-5-(4-bromo-2-fluorophenyl)-3-phenylpent-2-enoi...)
Affinity DataKd:  6.20E+3nMAssay Description:Binding affinity to PDK1 (50 to 359) by isothermal titration calorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed