BDBM50297037 3,6-Diamino-1-methyl-4-phenyl-1H-pyrazolo[3,4-b]pyridine-5-carbonitrile::CHEMBL552134::cid_851061

SMILES Cn1nc(N)c2c(-c3ccccc3)c(C#N)c(N)nc12

InChI Key InChIKey=HOBVNLOUQLAQOI-UHFFFAOYSA-N

Data  3 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50297037   

TargetHeat shock factor protein 1(Mus musculus)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM50297037(3,6-Diamino-1-methyl-4-phenyl-1H-pyrazolo[3,4-b]py...)
Affinity DataEC50: >1.95E+5nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Modified NIH3T3, transformed to express firefly...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetCyclin-dependent kinase 5(Homo sapiens (Human))
Laboratorio De Radicales Libres Y QuÍMica Computacional (Iqog, Csic)

Curated by ChEMBL
LigandPNGBDBM50297037(3,6-Diamino-1-methyl-4-phenyl-1H-pyrazolo[3,4-b]py...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human recombinant CDK5/P25 by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Laboratorio De Radicales Libres Y QuÍMica Computacional (Iqog, Csic)

Curated by ChEMBL
LigandPNGBDBM50297037(3,6-Diamino-1-methyl-4-phenyl-1H-pyrazolo[3,4-b]py...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human recombinant GST-fusion DYRK1A expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUbiquitin-conjugating enzyme E2 N(Homo sapiens (Human))
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM50297037(3,6-Diamino-1-methyl-4-phenyl-1H-pyrazolo[3,4-b]py...)
Affinity DataIC50: >2.00E+4nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego CA...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay