BDBM50297268 1-(2,3-Dihydro-indol-1-yl)-2-(5-methyl-1H-indol-3-yl)-ethane-1,2-dione::CHEMBL562198

SMILES Cc1ccc2[nH]cc(C(=O)C(=O)N3CCc4ccccc34)c2c1

InChI Key InChIKey=MATLTILJQXAUTC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50297268   

TargetCyclin-dependent kinase 2(Homo sapiens (Human))
University Of Leicester

Curated by ChEMBL
LigandPNGBDBM50297268(1-(2,3-Dihydro-indol-1-yl)-2-(5-methyl-1H-indol-3-...)
Affinity DataIC50:  9.51E+5nMAssay Description:Inhibition of human CDK2/ Cyclin A catalytic subunit expressed in Sf9 insect cells assessed as histone H1 phosphorylation-associated depletion in ATP...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 4(Homo sapiens (Human))
University Of Leicester

Curated by ChEMBL
LigandPNGBDBM50297268(1-(2,3-Dihydro-indol-1-yl)-2-(5-methyl-1H-indol-3-...)
Affinity DataIC50:  4.15E+4nMAssay Description:Inhibition of human CDK4/ Cyclin D1 catalytic subunit expressed in Sf9 insect cells assessed as GST-RB152 fusion protein phosphorylation-associated d...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed