BDBM50297349 1-Ethyl-4-fluoro-3-[(1S,2R)-2-hydroxy-3-(methylamino)-1-phenylpropyl]-1,3-dihydro-2H-benzimidazol-2-one::CHEMBL559610

SMILES CCn1c2cccc(F)c2n([C@H]([C@H](O)CNC)c2ccccc2)c1=O

InChI Key InChIKey=AJLUMLBNDXXSIW-SJORKVTESA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50297349   

TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50297349(1-Ethyl-4-fluoro-3-[(1S,2R)-2-hydroxy-3-(methylami...)
Affinity DataIC50:  11.4nMAssay Description:Inhibition of [3H]nisoxetine binding to human NET expressed in MDCK-Net6 cells by plate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50297349(1-Ethyl-4-fluoro-3-[(1S,2R)-2-hydroxy-3-(methylami...)
Affinity DataIC50:  13.8nMAssay Description:Inhibition of [3H]norepinephrine uptake at human NET expressed in MDCK-Net6 cells by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed