BDBM50297351 1-Ethyl-4-fluoro-3-[(1S,2R)-2-hydroxy-3-(methylamino)-1-(3-fluorophenyl)-propyl]-1,3-dihydro-2H-benzimidazol-2-one::CHEMBL560877
SMILES CCn1c2cccc(F)c2n([C@H]([C@H](O)CNC)c2cccc(F)c2)c1=O
InChI Key InChIKey=CTVFQEBCIXRGTI-SJORKVTESA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50297351
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Wyeth Research
Curated by ChEMBL
Wyeth Research
Curated by ChEMBL
Affinity DataIC50: 10.4nMAssay Description:Inhibition of [3H]norepinephrine uptake at human NET expressed in MDCK-Net6 cells by scintillation countingMore data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Wyeth Research
Curated by ChEMBL
Wyeth Research
Curated by ChEMBL
Affinity DataIC50: 4.10nMAssay Description:Inhibition of [3H]nisoxetine binding to human NET expressed in MDCK-Net6 cells by plate scintillation countingMore data for this Ligand-Target Pair