BDBM50297352 4-Fluoro-3-[(1S,2R)-1-(3-fluorophenyl)-2-hydroxy-3-(methylamino)-propyl]-1-isopropyl-1,3-dihydro-2H-benzimidazol-2-one::CHEMBL551474
SMILES CNC[C@@H](O)[C@H](c1cccc(F)c1)n1c2c(F)cccc2n(C(C)C)c1=O
InChI Key InChIKey=XWEOTQVRTMMRCV-MSOLQXFVSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50297352
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Wyeth Research
Curated by ChEMBL
Wyeth Research
Curated by ChEMBL
Affinity DataIC50: 4.10nMAssay Description:Inhibition of [3H]nisoxetine binding to human NET expressed in MDCK-Net6 cells by plate scintillation countingMore data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Wyeth Research
Curated by ChEMBL
Wyeth Research
Curated by ChEMBL
Affinity DataIC50: 6.90nMAssay Description:Inhibition of [3H]norepinephrine uptake at human NET expressed in MDCK-Net6 cells by scintillation countingMore data for this Ligand-Target Pair