BDBM50297352 4-Fluoro-3-[(1S,2R)-1-(3-fluorophenyl)-2-hydroxy-3-(methylamino)-propyl]-1-isopropyl-1,3-dihydro-2H-benzimidazol-2-one::CHEMBL551474

SMILES CNC[C@@H](O)[C@H](c1cccc(F)c1)n1c2c(F)cccc2n(C(C)C)c1=O

InChI Key InChIKey=XWEOTQVRTMMRCV-MSOLQXFVSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50297352   

TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50297352(4-Fluoro-3-[(1S,2R)-1-(3-fluorophenyl)-2-hydroxy-3...)
Affinity DataIC50:  4.10nMAssay Description:Inhibition of [3H]nisoxetine binding to human NET expressed in MDCK-Net6 cells by plate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50297352(4-Fluoro-3-[(1S,2R)-1-(3-fluorophenyl)-2-hydroxy-3...)
Affinity DataIC50:  6.90nMAssay Description:Inhibition of [3H]norepinephrine uptake at human NET expressed in MDCK-Net6 cells by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed