BDBM50297355 4-Fluoro-3-[(1S,2R)-2-hydroxy-3-(methylamino)-1-phenylpropyl]-1-isopropyl-1,3-dihydro-2H-benzimidazol-2-one::CHEMBL551473

SMILES CNC[C@@H](O)[C@H](c1ccccc1)n1c2c(F)cccc2n(C(C)C)c1=O

InChI Key InChIKey=DONMCIZYEUHXSH-MSOLQXFVSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50297355   

TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50297355(4-Fluoro-3-[(1S,2R)-2-hydroxy-3-(methylamino)-1-ph...)
Affinity DataIC50:  7.80nMAssay Description:Inhibition of [3H]norepinephrine uptake at human NET expressed in MDCK-Net6 cells by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed