BDBM50297357 1-Ethyl-5-fluoro-3-[(1S,2R)-2-hydroxy-3-(methylamino)-1-phenylpropyl]-1,3-dihydro-2H-benzimidazol-2-one::CHEMBL564445

SMILES CCn1c2ccc(F)cc2n([C@H]([C@H](O)CNC)c2ccccc2)c1=O

InChI Key InChIKey=DBNIRDAYCJINLF-MSOLQXFVSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50297357   

TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50297357(1-Ethyl-5-fluoro-3-[(1S,2R)-2-hydroxy-3-(methylami...)
Affinity DataIC50:  36.7nMAssay Description:Inhibition of [3H]norepinephrine uptake at human NET expressed in MDCK-Net6 cells by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed