BDBM50297723 (4-methylpiperidin-1-yl)(6-(3-(piperidin-1-yl)propoxy)naphthalen-2-yl)methanone::CHEMBL557461

SMILES CC1CCN(CC1)C(=O)c1ccc2cc(OCCCN3CCCCC3)ccc2c1

InChI Key InChIKey=PXUAIMJAHKAYPP-UHFFFAOYSA-N

Data  1 KI  5 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50297723   

TargetHistamine H3 receptor(Homo sapiens (Human))
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50297723((4-methylpiperidin-1-yl)(6-(3-(piperidin-1-yl)prop...)
Affinity DataKi:  7nMAssay Description:Inhibition of human histamine H3 expressed in CHO cells by saturation binding experimentMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50297723((4-methylpiperidin-1-yl)(6-(3-(piperidin-1-yl)prop...)
Affinity DataIC50: >1.20E+4nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50297723((4-methylpiperidin-1-yl)(6-(3-(piperidin-1-yl)prop...)
Affinity DataIC50: >1.20E+4nMAssay Description:Inhibition of CYP2C19More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50297723((4-methylpiperidin-1-yl)(6-(3-(piperidin-1-yl)prop...)
Affinity DataIC50: >1.20E+4nMAssay Description:Inhibition of CYP1A2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50297723((4-methylpiperidin-1-yl)(6-(3-(piperidin-1-yl)prop...)
Affinity DataIC50: >1.20E+4nMAssay Description:Inhibition of CYP2C9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50297723((4-methylpiperidin-1-yl)(6-(3-(piperidin-1-yl)prop...)
Affinity DataEC50:  200nMAssay Description:Inverse agonist activity at human histamine H3 receptor expressed in CHO cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50297723((4-methylpiperidin-1-yl)(6-(3-(piperidin-1-yl)prop...)
Affinity DataIC50: >1.20E+4nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed