BDBM50299060 (+/-)-2-[2-(4'-Methoxy-biphenyl-4-sulfonyl)phenyl]propionic Acid::CHEMBL584147

SMILES COc1ccc(cc1)-c1ccc(cc1)S(=O)(=O)c1ccccc1C(C)C(O)=O

InChI Key InChIKey=XORCBTCEBZUVES-UHFFFAOYSA-N

Data  9 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50299060   

TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50299060((+/-)-2-[2-(4'-Methoxy-biphenyl-4-sulfonyl)phenyl]...)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of para-aminophenylmercuric acetate-activated human recombinant pro-MMP9 catalytic domain after 4 hrs by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-14(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50299060((+/-)-2-[2-(4'-Methoxy-biphenyl-4-sulfonyl)phenyl]...)
Affinity DataIC50:  2.10E+3nMAssay Description:Inhibition of human recombinant pro-MMP14 catalytic domain after 4 hrs by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50299060((+/-)-2-[2-(4'-Methoxy-biphenyl-4-sulfonyl)phenyl]...)
Affinity DataIC50:  190nMAssay Description:Inhibition of para-aminophenylmercuric acetate-activated human recombinant pro-MMP2 catalytic domain after 4 hrs by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50299060((+/-)-2-[2-(4'-Methoxy-biphenyl-4-sulfonyl)phenyl]...)
Affinity DataIC50:  190nMAssay Description:Inhibition of para-aminophenylmercuric acetate-activated human pro-MMP13 after 4 hrs by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50299060((+/-)-2-[2-(4'-Methoxy-biphenyl-4-sulfonyl)phenyl]...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of para-aminophenylmercuric acetate-activated human pro-MMP1 after 4 hrs by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage metalloelastase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50299060((+/-)-2-[2-(4'-Methoxy-biphenyl-4-sulfonyl)phenyl]...)
Affinity DataIC50:  310nMAssay Description:Inhibition of autoactivated human pro-MMP12 after 4 hrs by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-16(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50299060((+/-)-2-[2-(4'-Methoxy-biphenyl-4-sulfonyl)phenyl]...)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of human recombinant pro-MMP16 catalytic domain after 4 hrs by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50299060((+/-)-2-[2-(4'-Methoxy-biphenyl-4-sulfonyl)phenyl]...)
Affinity DataIC50:  8.00E+3nMAssay Description:Inhibition of trypsin activated human pro-MMP3 after 4 hrs by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50299060((+/-)-2-[2-(4'-Methoxy-biphenyl-4-sulfonyl)phenyl]...)
Affinity DataIC50:  290nMAssay Description:Inhibition of para-aminophenylmercuric acetate-activated human pro-MMP8 after 4 hrs by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed